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- 公司名稱 上海玉研科學(xué)儀器有限公司
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當(dāng)前位置:儀器網(wǎng) > 產(chǎn)品中心 > 行業(yè)專用儀器>其它行業(yè)專用儀器>其它> (二合一)熱痛覺測(cè)量儀
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二合一熱痛覺測(cè)量儀包含足底痛覺測(cè)量儀和甩尾測(cè)痛儀:
二合一熱痛覺測(cè)量儀包含足底痛覺測(cè)量儀和甩尾測(cè)痛儀
Plantar Test Hargreaves Method 足底痛覺測(cè)量儀
Tail Flick Test Analgesia Meter Apparatus 甩尾測(cè)痛儀
型號(hào)390型+33型 或 390G型+33型
足底痛覺實(shí)驗(yàn)用于測(cè)試鎮(zhèn)痛藥物影響無束縛大鼠對(duì)外部熱刺激的反應(yīng)時(shí)間使用時(shí)先通過從爪下面的測(cè)試頭發(fā)出導(dǎo)向光將光源移到動(dòng)物爪底通過反光鏡確定位置避免頻繁彎腰和低頭方便操作啟動(dòng)加熱光束照射到動(dòng)物爪底進(jìn)行實(shí)驗(yàn)。
足底熱測(cè)痛儀主要特點(diǎn)
? 精確數(shù)字控制 時(shí)間精確度為0.01s
? 自動(dòng)切斷保護(hù)功能
? 光束強(qiáng)度可調(diào)節(jié)步進(jìn)量1%
? 手工結(jié)束測(cè)試減少誤觸發(fā)
? 強(qiáng)制取消定時(shí)器功能
? 數(shù)字顯示功能
? 動(dòng)物不需固定限制
? 加熱玻璃可選配
? 測(cè)試頭具有反光鏡輔助觀察
? 標(biāo)準(zhǔn)計(jì)算機(jī)打印口輸出
? 型號(hào)390 爪刺激痛覺測(cè)試儀
? 型號(hào)390G 爪刺激痛覺測(cè)試儀內(nèi)置熱玻璃
疼痛甩尾測(cè)試儀用于測(cè)試動(dòng)物疼痛反應(yīng)時(shí)間和動(dòng)物對(duì)鎮(zhèn)痛藥物的疼痛反應(yīng)極限。實(shí)驗(yàn)過程中檢測(cè)到動(dòng)物尾部甩動(dòng)后內(nèi)置的計(jì)時(shí)器自動(dòng)停止計(jì)時(shí)。
疼痛甩尾測(cè)試儀主要特點(diǎn)
? 實(shí)時(shí)尾部溫度/觸發(fā)可選
? 觸發(fā)溫度設(shè)置功能
? 精確數(shù)字控制時(shí)間精確度為0.01秒
? 自動(dòng)切斷保護(hù)功能
? 光束強(qiáng)度可調(diào)節(jié)步進(jìn)量1%
? 自動(dòng)檢測(cè)活動(dòng)反應(yīng)
? 強(qiáng)制取消定時(shí)器功能
? 數(shù)字顯示功能
? 標(biāo)準(zhǔn)計(jì)算機(jī)打印口輸出
The IITC Plantar Test Analgesia Meter for paw stimulation can be used on 12 mice, 6 rats and other animals (cats, rabbits) unrestrained when testing for narcotic drugs. Experiments are easy to perform, simply slide the test head under test subject, align the heat source via our exclusive guide light (idle state) by the attached, adjustable, angled mirror on test head to test subject and perform tests.
Start, stop and reset of tests is done by either the push button on test head, front panel controls or supplied footswitch.
With our exclusive “idle state” of the heat source one is assured of exact placement of the heat source. Tests are performed on the plantar surface by a focused, radiant heat light source. The light beam is focused to the top of the glass and creates a 4X6mm intense spot on the paw.
Our method of visible light is superior to the infrared light method, since a user will not always know exactly where/when the test will start, causing false starts and conditioning of animals. A built-in timer displays reaction time in .01 second increments.
The height of the glass is adjustable allowing the focal point of the light to be adjusted to stimulate other body parts if needed. A Humane cutoff timer is standard. The unit can be preset for a cutoff period, at the end of which the heat source shuts off automatically if the animal has not responded, avoiding tissue damage. Our test head does not emit , clicking or whining noises that cause preconditioning of animals prior to test as with other systems on the market.
Our exclusive heated glass option eliminates the glass acting as a heat sink. This feature will eliminate the reaction time of the animals to be altered due to the fact that they are placed on cold glass allowing the possibility of delayed response time to the applied heat source. Built-in heating elements in the glass which are digitally controlled for consistent temperatures. Temperature readout and adjustment from 30-40 degrees c. for the heated base is controlled on the heated base.
Tail Temperature Option Animal enclosure
Three individual, acrylic animal enclosures are supplied. Each enclosure allows for 2 rats/4 mice allowing testing of up to 6 rats/12mice total. Enclsoures have strong magnets to prevent animals from possible escape., individual lids, clear dividers in-between test subjects.
Tail Flick Test mode - the test head is attached to the electronic gear and the heat source now sits over a tail groove that has a sensor that detects the when the animal flicks it tail. System records and displays time and temperature of test. A humane cutoff timer that can be set by user, preventing tail tissue damage if test subject has not reacted within preset time.
TAIL TEMPERATURE OPTION (T)
Measurement of tail temperature at all times.
Trigger temperature is automatic at the start of every test.
This optional feature allows automatic preheating of the tail. To ensure experiment protocols to be precisely controlled and repeated. This feature allows the user to SET the tail temperature at start of each test is to be started at up to 75 degrees Celsius. Once that preset temperature is reached the test and the timer starts automatically and after the tail flicks the timer and light stop and the result is displayed. Readout will now show in repeatable sequence the start and end temperatures as well as test time.
We recommend animals be restrained with one of the IITC restrainers.
This unit solves the problem associated with “tail temperature prior to and at the end of testing.”
See articleKJELL HOLE AND ARNE TJOLSENThe Tail-Flick Formalin Test in RodentsChanges in Skin Temperature as a Confounding Factor.
Pain 53 (1993) pages. 247-254 Elsevier).
Features
Tail Temperature optional (T)
Precise Programmable digital control
Humane cut-off feature, set by user
Adjustable beam intensity in 1% increments
Reaction is detected automatically
(Tail Flick Test set-up)
Manual override of all timer functions
All Functions and parameters entered via key-pad
Heated glass option only from IITC
Footswitch - RS232 - Printer output (standard)
相關(guān)文獻(xiàn)
T Schneider, A Roman, A Basta-Kaim, M Kubera… - …, 2008 - Elsevier
… adverse developmental consequences produced by early brain injuries, especially in animal
models of human … valproic acid have not been studied in the presented animal model of autism …
withdrawal test carried out using an Analgesia Meter apparatus (Mod 33, IITC, INC, USA …
R Karlsten, C Post, I Hide, JW Daly - Neuroscience letters, 1991 - Elsevier
… The animals were used only once. Testing of tail flick was performed using an IITC Inc. Model
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T Schneider, R Przew?ocki - Neuropsychopharmacology, 2005 -
… The thermal paw withdrawal test was carried out using an Analgesia Meter apparatus (Mod 33,
IITC, Inc., USA) … aberrations described in this paper appear before puberty, which could distinguish the VPA rat model of autism from other animal models of psychiatric …
J Jurcovicova, M Stancikova, K Svik… - Clinical and …, 2001 - clinexprheumatol.org
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Y Yajima, M Narita, M Narita, N Matsumoto, T Suzuki - Brain research, 2002 - Elsevier
… each of the hind paws of mice was tested individually using a thermal stimulus apparatus (model
33 Analgesia Meter; IITC Inc./Life Science … An aliquot of tissue sample was diluted with an equal volume of electrophoresis sample buffer (Protein Gel Loading Dye-2x …
M Nishiyori, H Ueda - Molecular pain, 2008 -
… 10 μg in the neuropathic pain model, which is consistent with the previous study that … the ICS model is a promising candidate for experimental FMS or generalized pain syndrome models … thermal paw withdrawal test was carried out using a thermal stimulus (Model 33 Tail Flick …
M Kalinichev, KW Easterling, SG Holtzman - Psychopharmacology, 2001 - Springer
… an organism's responsiveness to stress has been exten- sively investigated in several rodent
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maternal … a light source was focused on the lower third of the tail (Model 33, Tail Flick …
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… PWL) in response to noxious thermal stimuli using an Analgesia Meter (mod 33, IITC INC., Landing, NJ … The initial phase of the CCI model of neuropathic pain involves inflammation around the nerve …restricted to the dorsal horns of the spinal cord, similar to previous studies [26 …
AR Gintzler, BR Komisaruk - Brain research, 1991 - Elsevier
… a lamp mounted 8 cm above the tail and was maintained until a response was elicited or 10 s
had elapsed (IITC Inc., Model 33, Landing, NJ) … Since in a previous study, there was no correlation between the magnitude of increase in TFL produced by vaginal stimulation and the …
YZ Gao, SY Guo, QZ Yin, T Hisamitsu… - The American journal of …, 2007 - World Scientific
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I Pekarkova, S Parara, V Holecek, P Stopka, L Trefil… - Physiol Res, 2001 - med.cas.cz
… It was found in our previous research in the field of pain that after repeated painful … The tail-flick test (TF) (Tail Flick Analgesia Meter Model 33, IITC Inc., Life Science Instruments, USA) measures the … Sample preparation On the last day of the experiment (the 5th day), after all the …
K Niikura, M Narita, M Narita, A Nakamura, D Okutsu… - Neuroscience …, 2008 - Elsevier
… paws of rats were tested individually using a thermal stimulus apparatus (model 33 Analgesia
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Consistent with many previous studies which have characterized afferent projections to …
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… Antinocieptive activity of Toddalia asiatica (L) Lam. in models of central and peripheral pain … Tail flick test A radiant heat tail-flick IITC Inc. Model 33 analgesiometer was used to measure response latencies according to the method described previously (Corrêa et al., 1996) …
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